The paper argues that compassionate psychedelic psychotherapy using psilocybin and MDMA can be morally permissible. When given under supportive conditions with psychotherapy, these therapies show promising results, but their controversial nature requires ethical justification. The authors review safety and efficacy and claim that it can be rational for some patients to try psychedelic therapy despite uncertainty, because the expected value can outweigh that of routine care, palliative care, or no care. They respond to the objection that psychedelic psychotherapy is epistemically harmful, arguing that this objection is unsubstantiated, mainly because no experimental evidence suggests such harm occurs.
Radical neurophenomenology rethinks the relationship between subjectivity and objectivity by using the concept of constitution to avoid dualistic frameworks. This paper argues that Merleau-Ponty's later work, especially his notion of the flesh, provides a suitable framework for elaborating a viable concept of co-constitution. Beyond theoretical analysis, the paper illustrates the pragmatic gain of this concept by showing how it should inform the understanding of modern neuroimaging techniques and qualitative phenomenological philosophy analysis of subjectivity and lived experience, thereby contributing to neurophenomenological inquiries.