Self-Reported Improvements in Comorbid Post-Traumatic Stress Disorder Symptoms, Depression, Anxiety, and Sleep Among Real-World Patients Receiving Medical Ketamine: Exploring the Role of Adjunct Therapies.
European journal of trauma & dissociation = Revue europeenne du trauma et de la dissociation September 1, 2025 Shahar Almog, Albert Garcia-Romeu, Kathryn A Walker et al. 1 citation
People with post-traumatic stress disorder (PTSD) who also have depression, anxiety, and sleep problems reported that ketamine treatment improved multiple PTSD symptoms, based on a survey of 202 real-world patients. Before starting ketamine, those with PTSD had more severe depression, anxiety, and sleep disturbance than those without PTSD, but after treatment their scores were no different, indicating they responded equally well. Most PTSD patients also received psychotherapy, but similar improvements occurred in those who did not. Patients described ketamine as allowing them to reprocess trauma and improve a range of symptoms.