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Temporal dynamics and long-term effects of a mindfulness-based intervention for young adults with adverse childhood experiences.

Diane Joss, Martin H. Teicher, Sara W. Lazar

Mindfulness September 1, 2024 DOI: 10.1007/s12671-024-02439-x via PubMed

Summary

AI-generated from the abstract

Mindfulness-based interventions (MBIs) produce unique therapeutic effects for young adults with adverse childhood experiences, with improvements in trait mindfulness driving reductions in perceived stress, somatization, and hostility. In a clinical trial, 21 participants completed an 8-week MBI and 19 completed a stress management education control. Weekly and follow-up assessments over 18 months showed that mindfulness increases began at the end of the 8-week program, and most symptom reductions lasted 12 months without refresher courses. Only the MBI group showed mindfulness gains predicting later symptom decreases. The findings suggest that at least 8 weeks of MBI and a refresher at 12 months may be needed for lasting benefit.

Study at a glance

Characteristics Randomized controlled trial Longitudinal Preregistered Peer reviewed
Sample size 40
Population Young adults aged 21-35 with adverse childhood experiences
Interventions Mindfulness-based intervention Stress Management Education
Duration 8-week intervention, 6-, 12-, and 18-months follow-up
Topics Depression
Keywords Causal inference Long term Somatization Stress
Citations 11
Key finding Mindfulness-based intervention led to increases in trait mindfulness that predicted reductions in perceived stress, somatization, and hostility, with most symptom reductions lasting 12 months.

Abstract

Mindfulness-based interventions (MBIs) have been shown to be beneficial for young adults with adverse childhood experiences (ACE), but the temporal course of the therapeutic effects is still not well understood. This study aimed to investigate MBI-induced weekly changes and long-term effects in trait mindfulness and psychological symptoms. This study analyzed longitudinal data from a mechanistic clinical trial in which young adults (aged 21-35) with ACE were randomized to an 8-week MBI or an active control condition of Stress Management Education (SME), with 21 and 19 completers respectively. Mindful Attention Awareness Scale (MAAS), Perceived Stress Scale (PSS), and Kellner's Symptom Questionnaire (KSQ) were administered before, after, and weekly during the 8-week interventions, and at 6-, 12-, and 18-months follow-up. Data analyses were conducted with linear mixed effects models, Granger causality and Dynamic Structural Equation Modeling (DSEM). Group by time interaction effects were observed with PSS, MAAS, KSQ-depression, KSQ-hostility, and KSQ-anxiety with small effect sizes. Only in the MBI group, increases of MAAS scores predicted reductions of PSS, KSQ-somatization, and KSQ-hostility scores. MAAS score reached significant increase at the end of MBI, and most MBI-induced symptom reduction lasted 12 months without refresher courses. MBI demonstrated unique effects of trait mindfulness improvement leading to psychological symptom reductions. At least 8 weeks of MBI program duration and refreshment at 12 months may be necessary for ACE survivors. This study is not preregistered.

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