Meditation and Cognitive Outcomes: A Longitudinal Analysis Using Data From the Health and Retirement Study 2000-2016.
Snehal Lopes, Lu Shi, Xi Pan, Yian Gu, Christine Dengler-Crish, Yan Li, Biplav Tiwari, Donglan Zhang
Mindfulness July 1, 2023 DOI: 10.1007/s12671-023-02165-w via PubMed
Summary
AI-generated from the abstractAmong 1,160 middle-aged and older adults from the Health and Retirement Study, meditating at least twice a week was not associated with changes in recall, global cognitive function, or quantitative reasoning over 16 years. However, among participants without depressive symptoms at the start, frequent meditation was linked to improvements in total recall and global cognitive function over time. The findings suggest that meditation may protect cognitive function only in those without baseline depressive symptoms.
Study at a glance
| Characteristics | Observational cohort Randomized Longitudinal Preregistered Peer reviewed |
|---|---|
| Sample size | 1,160 |
| Population | Middle-aged and older adults from the Health and Retirement Study |
| Intervention | Meditation |
| Duration | 16-year follow-up (2000-2016) |
| Topics | Meditation |
| Keywords | Aging Cognition |
| Citations | 5 |
| Key finding | Frequent meditation was associated with improved recall and global cognitive function over time only among participants without baseline depressive symptoms. |
Abstract
We aimed to assess the association between meditation practice and cognitive function over time among middle-aged and older adults. We included Health and Retirement Study (HRS) participants assessed for meditation practice in the year 2000 as part of the HRS alternative medicine module (n = 1,160) and were followed up for outcomes over 2000-2016 period. We examined the association between meditation ≥ twice a week vs none/less frequent practice and changes in the outcomes of recall, global cognitive function, and quantitative reasoning using generalized linear regression models. Stratified analyses among persons with/without self-reported baseline depressive symptoms were conducted to assess the link between meditation and cognitive outcomes. Among our full study sample, meditation ≥ twice a week was not significantly associated with total recall [β; 95% CI: -0.97, 0.57; p = 0.61], global cognitive function [β; 95% CI: -1.01, 1.12; p = 0.92], and quantitative reasoning [β; 95% CI: -31.27, 8.32; p = 0.26]. However, among those who did not have self-reported depressive symptoms at baseline, meditation ≥ twice a week was associated with improvement in cognitive outcomes such as total recall [β; 95% CI: 0.03, 0.18; p = 0.01] and global cognitive function [β; 95% CI: 0.05, 0.40; p = 0.01] over time. Frequent meditation practice might have a protective effect on cognitive outcomes over time, but this protection could be limited to those without self-reported baseline depressive symptoms. Future studies could incorporate more precise meditation practice assessment, investigate the effect of meditation on cognitive outcomes over time, and include more rigorous study designs with randomized group assignment. This study is not preregistered.