Hallucinations Under Psychedelics and in the Schizophrenia Spectrum: An Interdisciplinary and Multiscale Comparison
Pantelis Leptourgos, Martin Fortier-Davy, Robin Carhart‐Harris, Philip R. Corlett, David Dupuis, Adam L. Halberstadt, Michael Kometer, Eva Kozáková, Frank Larøi, Tehseen Noorani, Katrin H. Preller, Flavie Waters, Yuliya Zaytseva, Renaud Jardri
Schizophrenia Bulletin August 5, 2020 DOI: 10.1093/schbul/sbaa117 via OpenAlex
Summary
AI-generated from the abstractA multidisciplinary working group reviewed evidence on the similarities and differences between hallucinations induced by psychedelics and those occurring in schizophrenia-spectrum disorders, examining data from pharmacology, brain imaging, phenomenology, and anthropology. The authors highlight both shared features and distinct characteristics across these scales, and attempt to integrate findings using computational approaches. They conclude with recommendations for future research, emphasizing the need for further study to clarify the relationship between these types of hallucinations.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Psilocybin |
| Keywords | Psychosis Schizophrenia spectrum Multidisciplinary approach Schizophrenia object-oriented programming The renaissance |
| Citations | 88 |
| Key finding | Hallucinations under psychedelics and in schizophrenia-spectrum disorders show both similarities and differences across pharmacological, neural, phenomenological, and anthropological levels of analysis. |
Abstract
Abstract The recent renaissance of psychedelic science has reignited interest in the similarity of drug-induced experiences to those more commonly observed in psychiatric contexts such as the schizophrenia-spectrum. This report from a multidisciplinary working group of the International Consortium on Hallucinations Research (ICHR) addresses this issue, putting special emphasis on hallucinatory experiences. We review evidence collected at different scales of understanding, from pharmacology to brain-imaging, phenomenology and anthropology, highlighting similarities and differences between hallucinations under psychedelics and in the schizophrenia-spectrum disorders. Finally, we attempt to integrate these findings using computational approaches and conclude with recommendations for future research.