Sublethal Concentrations of 2C-I and 25I-NBOMe Designer Drugs Impact Caenorhabditis elegans Development and Reproductive Behavior.
Eva Gil-Martins, Daniel José Barbosa, Fernando Cagide, Fernando Remião, Fernanda Borges, Renata Silva
Int J Mol Sci March 26, 2025 DOI: 10.3390/ijms26073039 via PubMed Central
Summary
AI-generated from the abstractSublethal concentrations of the designer drugs 2C-I and 25I-NBOMe impair development and reproductive behavior in the roundworm Caenorhabditis elegans. Exposed worms showed delayed growth and altered egg-laying patterns, indicating that even low, non-lethal doses of these substances can disrupt key biological processes. The findings suggest potential developmental and reproductive risks from these drugs.
Study at a glance
| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Caenorhabditis elegans |
| Interventions | 2C-I 25I-NBOMe |
| Keywords | Designer drugs C. elegans Biological effects |
| Key finding | Sublethal concentrations of 2C-I and 25I-NBOMe impair development and reproductive behavior in Caenorhabditis elegans. |
Abstract
Sublethal Concentrations of 2C-I and 25I-NBOMe Designer Drugs Impact Caenorhabditis elegans Development and Reproductive Behavior.