Biomedical Significance of Tryptamine: A Review
Shazia Kousara, Sadia Noreen Anjuma, Farrukh Jaleel, Jallat Khana, Sidra Naseema
Journal of Pharmacovigilance January 1, 2017 DOI: 10.4172/2329-6887.1000239 via OpenAlex
Summary
AI-generated from the abstractTryptamine, a psychotropic compound with an indole ring, has broad biological and pharmaceutical significance. This review covers recent achievements of tryptamine and its natural and synthetic derivatives as neurotransmitters, neuromodulators, vasoconstrictors, vasodilators, antimicrobial, antibacterial, antioxidant, and antifungal agents. The authors comprehensively survey the variety of biological activities reported in these areas.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Keywords | Tryptamine Antifungal Pharmacology Medicine Chemistry |
| Citations | 41 |
| Key finding | Tryptamine and its derivatives exhibit diverse biological activities including neurotransmitter, vasoactive, antimicrobial, antioxidant, and antifungal effects. |
Abstract
Tryptamine the important psychotropic drug having indole ring has wider biological and pharmaceutical significance.The focus is to see the relevant and recent achievements as neurotransmitter and neuromodulator, vasoconstrictor and vasodilator, antimicrobial and antibacterial, antioxidant and antifungal agents.Tryptamine and its natural and synthetic derivative have been reported for the variety of biological significance in the above mentioned area.This review covers all these aspects in a comprehensive way.