Psychotherapy Process Dynamics and Their Relation to Treatment Success Do Not Differ Across Diagnoses.
Lennart Seizer, Leonhard Kratzer, Johanna Löchner, Helmut Schöller, Wolfgang Aichhorn, Günter Schiepek
Clinical psychology & psychotherapy January 1, 2026 DOI: 10.1002/cpp.70222 via PubMed
Summary
AI-generated from the abstractPsychiatric inpatients with depression, PTSD, dissociative disorders, or personality disorders completed a therapy process questionnaire each evening for an average of 81.5 days. Eight dynamic process characteristics—such as variability, autocorrelation, instability, and complexity—were computed for each patient. No significant differences in these characteristics or their change over time were found across diagnostic groups, suggesting that individual within-person patterns overshadow diagnostic distinctions. Clinical improvement was linked to rising average levels and declining variability in positive emotions, mindfulness, insight, and motivation, and these predictions were not moderated by diagnosis. The findings support a transdiagnostic approach to measurement-based care that uses individual process characteristics to guide interventions.
Study at a glance
| Characteristics | Observational cohort Longitudinal Peer reviewed |
|---|---|
| Sample size | 283 |
| Population | Psychiatric inpatients diagnosed with depression, PTSD, dissociative disorders, or personality disorders |
| Duration | Average of 81.5 days per patient |
| Keywords | Ambulatory assessment Diagnostic categories Dynamic pattern Ecological momentary assessment Monitoring |
| Citations | 1 |
| Key finding | No significant differences in dynamic process characteristics or their change over time were found across diagnostic groups, and clinical improvement was associated with rising mean levels and declining variability in positive emotions, mindfulness, insight, and motivation, regardless of diagnosis. |
Abstract
Psychotherapy process research increasingly uses intensive longitudinal monitoring to capture dynamic patterns of change in patients. In this study, 283 psychiatric inpatients diagnosed with depression (n = 70), PTSD (n = 148), dissociative disorders (n = 26) or personality disorders (n = 39) completed the Therapy Process Questionnaire each evening over an average of 81.5 days per patient, yielding a total of 23,074 assessment days. We computed eight dynamic process characteristics, including variability, autocorrelation, instability and complexity, for each TPQ scale, both on average per patient and in a moving-window approach. Then, the diagnostic groups were compared via one-way ANOVAs with Bonferroni-Holm correction. No significant differences emerged across diagnoses in any average process characteristics or their change over time, indicating that idiosyncratic within-person process dynamics overshadow diagnostic distinctions. Further, patients' clinical improvement was associated with rising mean levels and declining variability in positive emotions, mindfulness, insight and motivation. Again, these predictions of improvement were not moderated by patients' diagnoses. Our results support a transdiagnostic approach to measurement-based care that leverages individual process characteristics to guide interventions, rather than relying on diagnostic categories to predict therapy trajectories.