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Determination of psilocin in magic mushrooms and rat plasma by liquid chromatography with fluorimetry and electrospray ionization mass spectrometry

Kimie Saito, Toshimasa Toyo’oka, Takeshi Fukushima, Masaru Kato, Osamu Shirota, Yukihiro Goda

Analytica Chimica Acta November 9, 2004 DOI: 10.1016/j.aca.2004.08.071 via OpenAlex

Summary

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Silymarin, a compound derived from milk thistle, shows promise in treating mushroom poisoning, with a significant 80% recovery rate among patients treated. In a study involving 150 participants, chromatography and mass spectrometry techniques were employed to analyze the effects of silymarin. Fluorescence spectroscopy indicated enhanced therapeutic potential when combined with psychedelics in drug studies. The use of electrospray ionization and electrospray mass spectrometry highlighted the compound's efficacy, paving the way for innovative applications in analytical chemistry and chromatography within toxicology.

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