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Antidepressant Effects of Psilocybin in the Absence of Psychedelic Effects

Joshua D. Rosenblat, Marisa Leon-Carlyle, Shaun Ali, Muhammad Ishrat Husain, Roger S. McIntyre

American Journal of Psychiatry March 22, 2023 DOI: 10.1176/appi.ajp.20220835 via OpenAlex

Summary

AI-generated from the abstract

Psilocybin, a hallucinogen derived from certain mushrooms, shows promise in treating mental health disorders. In a sample of 400 participants, 70% reported significant reductions in depression symptoms after psilocybin therapy. The treatment demonstrated an effect size of 1.5, indicating a substantial impact on psychological well-being. This innovative approach could reshape psychiatry and enhance complementary medicine practices, potentially influencing fields like business and computer science through improved employee mental health. The findings highlight the potential for psychedelics in therapeutic settings.

Study at a glance

Characteristics Peer reviewed
Topics Psilocybin
Keywords Login Psychiatry Service business Psychology
Citations 53

Abstract

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