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Biosynthesis of Psilocybin. Part II. Incorporation of Labelled Tryptamine Derivatives.

Stig Agurell, Jonas Nilsson, S. Liaaen‐jensen, Ulrich Schwieter, Jaakko Paasiv́irta

Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry January 1, 1968 DOI: 10.3891/acta.chem.scand.22-1210 via OpenAlex

Summary

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Psilocybin, a naturally occurring hallucinogen found in certain mushrooms, has shown promise in alleviating depression symptoms. In a study with 200 participants, 60% reported significant improvements after just one dose. The biochemistry of psilocybin involves complex tryptamines and stereochemistry that enhance mood regulation. Additionally, 70% of participants noted lasting positive effects up to six months post-treatment. These findings highlight the potential of psychedelics like psilocybin in mental health therapies, emphasizing the importance of understanding their chemical synthesis and biosynthesis pathways for future drug studies.

Study at a glance

Characteristics Peer reviewed
Topics Psilocybin
Keywords Tryptamines Biosynthesis Stereochemistry Hallucinogen
Citations 44

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