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Differences Between the Mechanism of Action of MDMA, MBDB, and the Classic Hallucinogens. Identification of a New Therapeutic Class: Entactogens

David E. Nichols

Journal of Psychoactive Drugs October 1, 1986 DOI: 10.1080/02791072.1986.10472362 via OpenAlex

Summary

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MDMA, MBDB, and classic hallucinogens have distinct mechanisms of action. MDMA and MBDB produce a unique psychological profile characterized by enhanced empathy and emotional openness, differing from both stimulants and hallucinogens. This profile defines a new therapeutic class called entactogens. The paper argues that entactogens, by their specific neurochemical effects, offer potential for psychotherapy distinct from that of classic hallucinogens or amphetamines.

Study at a glance

Characteristics Theoretical or philosophical paper Peer reviewed
Topics MDMA
Keywords Hallucinogen Psychology Identification biology Mechanism biology
Citations 568
Key finding MDMA and MBDB define a new therapeutic class, entactogens, with a mechanism of action and psychological profile distinct from classic hallucinogens and stimulants.

Abstract

(1986). Differences Between the Mechanism of Action of MDMA, MBDB, and the Classic Hallucinogens. Identification of a New Therapeutic Class: Entactogens. Journal of Psychoactive Drugs: Vol. 18, MDMA: Proceedings of the Conference, pp. 305-313.

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