Chemistry and Pharmacology of Hallucinogens, Entactogens and Stimulants
Pharmacopsychiatry July 1, 1998 DOI: 10.1055/s-2007-979349 via OpenAlex
Summary
AI-generated from the abstractAmphetamines, tryptamines, phencyclidines, tetrahydrocannabinol, and ecstasy-group substances are classified as stimulants, hallucinogens, and entactogens. Their effects and mechanisms in different neurotransmitter systems are described. Twenty-eight new compounds in the amphetamine and tryptamine series have been calculated to have hallucinogenic effects exceeding those of mescaline. The distinct metabolic pathways of MDMA (ecstasy) and MDE in humans may account for their individual effects.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Topics | MDMA Mescaline Psilocybin |
| Keywords | Hallucinogen Tryptamines |
| Citations | 32 |
| Key finding | Twenty-eight new amphetamine and tryptamine compounds are calculated to have hallucinogenic effects greater than mescaline. |
Abstract
Amphetamines, tryptamines, phencyclidines, tetrahydrocannabinol and substances of the ecstasy group are characterized as stimulants, hallucinogens and entactogens. The various effects of each group and their mode of action in different transmitter systems are described. 28 new compounds of the amphetamine and tryptamine series has been calculated, which exceed the hallucinogenic effects of mescaline. The different pathways of the metabolism of MDMA (ecstasy) and MDE in humans may probably explain their individual effects.