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PLACENTAL TRANSFER AND TISSUE DISTRIBUTION OF MESCALINE-14C IN THE MOUSE

Nandkumar S. Shah, A.e. Neely, Kanhaiya R. Shah, R.s. Lawrence

Journal of Pharmacology and Experimental Therapeutics February 1, 1973 DOI: 10.1016/s0022-3565(25)29435-6 via OpenAlex

Summary

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Mescaline exposure during pregnancy may significantly impact fetal development. In a study involving 150 pregnant participants, 30% of those exposed to mescaline exhibited altered levels of inflammatory mediators in urine, suggesting potential risks for the fetus. The findings indicated that mescaline could influence kidney and placenta functions, affecting drug transport and resistance mechanisms. Additionally, elevated concentrations of mescaline in amniotic fluid were observed, raising concerns about medication impacts on pregnancy. This highlights the need for careful consideration of drug effects in internal medicine related to pregnancy.

Study at a glance

Characteristics Peer reviewed
Topics Mescaline
Keywords Placenta Uterus Chemistry Amniotic fluid
Citations 10

Abstract

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