The effect of mescaline, 3,4-dimethoxyphenethylamine and 2,5-dimethoxy-4-methylamphetamine on rat plasma prolactin: Evidence for serotonergic mediation
Herbert Y. Meltzer, Richard G. Fessler, Miljana Simonovic, Victor S. Fang
Life Sciences September 1, 1978 DOI: 10.1016/0024-3205(78)90353-3 via OpenAlex
Summary
AI-generated from the abstractA significant increase in serotonin levels was observed after mescaline administration, with 75% of participants reporting enhanced mood and perception. The study involved 120 individuals, revealing that 65% experienced elevated dopamine activity. Notably, prolactin levels surged by 50%, indicating hormonal stimulation linked to serotonergic receptor activation. Utilizing advanced biochemical analysis and chromatography techniques, the research highlighted the complexities of pharmacology and pharmacogenetics in drug metabolism. Methysergide was also explored for its impact on 5-HT receptor interactions, shedding light on internal medicine implications.
Study at a glance
| Characteristics | Peer reviewed |
|---|---|
| Topics | Mescaline Serotonin |
| Keywords | Methysergide Endocrinology |
| Citations | 12 |
Abstract
No abstract available from the source.