A relationship between hexobarbitone sleeping time and susceptibility to mescaline in mice from different strains
Psychopharmacology January 1, 1975 DOI: 10.1007/bf00429260 via OpenAlex
Summary
AI-generated from the abstractMale mice from seven inbred strains (A2G, C57BR, C3H, F/st, CBA, ICFW, and Schneider) were tested for hexobarbitone sleeping time. The same strains had previously been tested for the inhibitory effect of mescaline on emotional defecation. A strong correlation between the two measures across strains was found, which was unexpected theoretically and may have important implications for pharmacogenetics.
Study at a glance
| Characteristics | Observational study Peer reviewed |
|---|---|
| Population | Male mice from seven inbred strains |
| Interventions | hexobarbitone mescaline |
| Topics | Mescaline |
| Keywords | Psychology Correlation Biology |
| Citations | 2 |
| Key finding | There is a strong interstrain correlation between hexobarbitone sleeping time and the inhibitory effect of mescaline on emotional defecation. |
Abstract
Males from the following strains were surveyed with respect to their hexobarbitone sleeping time: A2G, C57BR, C3H, F/st, CBA, ICFW and Schneider. Males from the same strains had previously been surveyed with respect to the inhibitory effect of mescaline on their emotional defaecation. There is a strong interstrain correlation between the 2 measures. This correlation was unexpected on theoretical grounds and may have important pharmacogenetic implications.