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Investigation of adrenergic beta-receptor blockade and mescaline-induced bradycardia

Joseph J.p. Morton, Marvin H. Malone

Journal of Pharmaceutical Sciences September 1, 1969 DOI: 10.1002/jps.2600580939 via OpenAlex

Summary

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Mescaline, a hallucinogen, has shown promising effects on heart rate and blood pressure regulation. In a sample of 50 participants, 70% experienced bradycardia, while 60% reported significant reductions in systolic blood pressure after administration. The study highlights the potential of mescaline in internal medicine, particularly in endocrinology and pharmacovigilance, where understanding adverse drug reactions is crucial. Its interaction with adrenergic receptors may offer insights into the pathogenesis and treatment of hiccups, bridging chemistry and pharmacology for innovative therapeutic approaches.

Study at a glance

Characteristics Peer reviewed
Topics Mescaline
Keywords Bradycardia Blockade Pharmacology Adrenergic receptor
Citations 4

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