Implementing psilocybin-assisted therapy in palliative care settings: A survey of stakeholders

Most palliative care stakeholders in Canada view psilocybin-assisted therapy favorably, with 95% of physicians reporting positive attitudes. A cross-sectional online survey of 121 adults involved in palliative care found that the lack of trained healthcare providers is the primary barrier to implementation, while further research and standardized protocols are key facilitators. Sixty-eight percent of stakeholders support introducing this therapy early in the illness trajectory. The findings highlight significant divergence in perspectives between clinical and non-clinical groups, suggesting tailored interprofessional education could build shared understanding. The study's Canadian context may limit transferability to other regulatory frameworks.

Study at a glance

Abstract

BACKGROUND: While the adoption of psilocybin-assisted therapy for existential distress offers promising support for patients with life-threatening illnesses, implementing this intervention into palliative care settings presents significant real-world challenges. AIM: To examine palliative care stakeholders' knowledge and attitudes regarding psilocybin-assisted therapy, and identify barriers and facilitators to its implementation. DESIGN: We conducted a cross-sectional online survey between April 15 and December 18, 2024. The survey assessed perceived knowledge, attitudes, and perceived barriers and facilitators to the effective integration of psilocybin-assisted therapy into palliative care settings. SETTING/PARTICIPANTS: One hundred and twenty-one adults involved in palliative care (physicians, other healthcare professionals, caregivers, and managers) were recruited from Canada's four most populous provinces: Québec, Ontario, Alberta, and British Columbia. RESULTS: < 0.0001), with 95% of physicians reporting favourable attitudes. The lack of trained healthcare providers was viewed as the primary barrier to implementation. Key facilitators included further research and developing standardised intervention protocols. Sixty-eight percent of stakeholders endorsed the introduction of psilocybin-assisted therapy during the early stages of the illness trajectory. CONCLUSIONS: Translating the potential of psilocybin-assisted therapy for existential distress from clinical trials into palliative care settings requires careful consideration and collaboration with stakeholders. Given the significant divergence in perspectives between clinical and non-clinical groups, tailored interprofessional education could help build shared understanding and support effective implementation. Being conducted in Canada, transferability to different regulatory frameworks may be limited.