The Role of Psilocybin in End-of-Life Care: Evidence, Mechanisms, and Guidelines

Psilocybin shows promise in end-of-life care by reducing anxiety and depression. Evidence from clinical trials suggests it can improve psychological and spiritual well-being in terminally ill patients. The article reviews the mechanisms behind these effects and offers practical guidelines for clinicians to assess patient use and safely integrate psilocybin into practice, while respecting its current legal status in the United States.

Study at a glance

Abstract

This article aims to provide a brief overview of the evidence and mechanisms for psilocybin use in EOL care. Additionally, this article will provide guidelines for clinicians to assess patient use and integrate psilocybin into their clinical practice with respect to its current legal status.