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A cross-sectional survey on depersonalization/derealization and meditation-induced alterations of the self.

Erola Pons, Julieta Galante, Nicholas T Van Dam, Axel Lindner

Scientific reports May 8, 2026 DOI: 10.1038/s41598-026-51014-y via PubMed

Summary

AI-generated from the abstract

Depersonalization and derealization (DPDR) involve feeling detached from one's body, thoughts, or emotions, typically triggered by trauma, stress, or drugs and causing high distress. Similar experiences arise during meditation, where they are often described as positive and meaningful. This cross-sectional study compared DPDR-like states triggered by meditation (60 participants) versus other triggers (61 participants). The meditation-triggered group rated their experiences as substantially more positive, though most participants in both groups described them as mixed. Meditation-induced DPDR occurred across types and experience levels. These experiences are phenomenologically similar but more welcome, pleasant, and spiritually meaningful than those from trauma or cannabis, though distress is not uncommon. Contemplative approaches may inform clinical support for DPDR, and guidance within meditation settings is needed.

Study at a glance

Characteristics Cross-sectional study Preregistered Peer reviewed
Sample size 121
Population Adults who had experienced DPDR-like states triggered through meditation or other triggers
Topics Ego dissolution Meditation
Keywords Depersonalization Derealization Mental health
Key finding Meditation can induce states phenomenologically similar to DPDR, but these are experienced as more positive, welcome, and spiritually meaningful than those triggered by trauma, stress, or cannabis, though distress is not uncommon.

Abstract

Depersonalization/derealization (DPDR) involves feeling detached from one's body, thoughts, or emotions and is often triggered by trauma, stress, mental health issues, or drug use, typically causing high distress. Similar experiences are also reported in meditation contexts, where they are often described as positive, insightful, and meaningful. However, no study has systematically compared DPDR-like experiences across these contexts. This preregistered, cross-sectional study addresses this gap. Participants who had experienced DPDR-like states triggered through meditation (MEDT, n = 60) or through other triggers (NMEDT, n = 61) completed five questionnaires and provided additional information about their DPDR experience and meditation practice. The two groups significantly differed on all questionnaires except the Cambridge Depersonalisation Scale, including its subscales covering different DPDR aspects. The MEDT group rated their experiences as substantially more positive than NMEDT, though most participants in both groups described them as mixed. In MEDT, these experiences were reported across meditation types and experience levels. Overall, meditation can induce states phenomenologically similar to DPDR, but these are often experienced as more welcome, pleasant, and spiritually meaningful than those triggered by trauma, stress, or cannabis, although distress is not uncommon. These findings suggest contemplative approaches may inform clinical support for DPDR, while highlighting the need for recognition and guidance within meditation settings.

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