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Acute renal injury cause by confirmed Psilocybe cubensis mushroom ingestion.

Emily Austin, Hilary S Myron, Richard K Summerbell, Connie Mackenzie

Medical mycology case reports March 1, 2019 DOI: 10.1016/j.mmcr.2018.12.007 via PubMed

Summary

AI-generated from the abstract

A 15-year-old male developed acute kidney injury 36 hours after consuming Psilocybe cubensis mushrooms, with symptoms including hypertension, nausea, and abdominal pain, and a creatinine level of 450 mmol/L. The mushrooms were confirmed by mass spectrometry to contain psilocin. He was hospitalized and discharged on day 5, with follow-up showing complete recovery of kidney function. This is the first reported case of acute kidney injury linked to confirmed ingestion of this mushroom species, though adverse effects from psilocybe mushrooms are generally rare.

Study at a glance

Characteristics Case study Case report Peer reviewed
Sample size 1
Population 15-year-old male
Keywords Kidney injury Mushrooms Nephrotoxicity Psilocybe
Citations 16
Key finding Confirmed ingestion of Psilocybe cubensis mushrooms can cause acute kidney injury, which resolved completely in this patient.

Abstract

Psilocybe mushrooms are consumed for their hallucinogenic properties. Fortunately, there are relatively few adverse effects associated with their consumption. This is the first reported case of acute kidney injury (AKI) secondary to confirmed ingestion of Psilocybe cubensis mushroom. A 15-year-old male developed symptomatic AKI 36 h post-ingestion of Psilocybe cubensis mushrooms. He was admitted to hospital with hypertension, nausea and abdominal pain and a creatinine of 450 mmol/L. A sample of the crop of mushrooms was confirmed by mass spectrometry to contain psilocin. On day 5 post-admission, he was discharged home. Outpatient follow-up confirmed complete resolution of his renal function.

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