Ketamines for Treatment Resistant Depression in Patients with Chronic Pain and Opioid Use
Michael Hart, Zack Z. Cernovsky
Archives of Psychiatry and Behavioral Sciences January 1, 2019 DOI: 10.22259/2638-5201.0202008 via OpenAlex
Summary
AI-generated from the abstractKetamine shows promise for treating major depression in patients who have not responded to standard antidepressants, including those with a history of chronic pain. The findings suggest that ketamine's rapid antidepressant effects may be particularly beneficial for this difficult-to-treat population, though the exact mechanisms remain under investigation.
Study at a glance
| Characteristics | Peer reviewed |
|---|---|
| Population | Patients with history of chronic pain and treatment-resistant major depression |
| Intervention | Ketamine |
| Keywords | Depression economics Chronic pain Opioid Internal medicine Psychiatry |
| Citations | 1 |
| Key finding | Ketamine may be effective for treating major depression in patients with a history of chronic pain who have not responded to standard antidepressants. |
Abstract
present study extends the application of ketamine to patients with history of not only chronic