Ketamines for Treatment Resistant Depression in Patients with Chronic Pain and Opioid Use
Archives of Psychiatry and Behavioral Sciences January 1, 2019 Michael Hart, Zack Z. Cernovsky 1 citation
Ketamine shows promise for treating major depression in patients who have not responded to standard antidepressants, including those with a history of chronic pain. The findings suggest that ketamine's rapid antidepressant effects may be particularly beneficial for this difficult-to-treat population, though the exact mechanisms remain under investigation.