Characterization and prediction of acute and sustained response to psychedelic psilocybin in a mindfulness group retreat.
Lukasz Smigielski, Michael Kometer, Milan Scheidegger, Rainer Krähenmann, Theo Huber, Franz X. Vollenweider
Sci Rep October 24, 2019 DOI: 10.1038/s41598-019-50612-3 via PubMed Central
Summary
AI-generated from the abstractIn a mindfulness group retreat setting, the acute and sustained effects of psilocybin were characterized and predicted. The study examined how individuals responded to the psychedelic during and after the retreat, identifying factors that influenced the strength and duration of the experience. Results showed that certain psychological and contextual variables predicted more profound acute responses, which in turn were associated with greater long-term improvements in well-being. The findings suggest that psilocybin's effects in a group mindfulness context are shaped by individual differences and the retreat environment, offering insights into optimizing therapeutic use.
Study at a glance
| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Population | Participants in a mindfulness group retreat |
| Intervention | Psilocybin |
| Topics | Meditation Psilocybin |
| Keywords | Psychedelics Hallucinogens |
| Citations | 174 |
| Key finding | Acute response to psilocybin in a mindfulness retreat setting predicted sustained improvements in well-being, with individual and contextual factors influencing the experience. |
Abstract
Characterization and prediction of acute and sustained response to psychedelic psilocybin in a mindfulness group retreat.