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Identification of seven psychedelic 2,5-dimethoxy-phenylethyl-amine-based designer drugs via benchtop 1 H nuclear magnetic resonance spectroscopy.

Juan F Araneda, Marion Baumgarte, Marie Lange, Alexander F G Maier, Susanne D Riegel

Magnetic resonance in chemistry : MRC February 1, 2023 DOI: 10.1002/mrc.5205 via PubMed

Summary

AI-generated from the abstract

Benchtop NMR spectroscopy at 60 MHz can distinguish seven members of the 2C-X series of new psychoactive substances (2C-B, 2C-C, 2C-D, 2C-E, 2C-P, 2C-T2, and 2C-T7) based on their proton NMR spectra. The molecular structural relationships among these compounds are reflected in their spectral patterns, supporting the use of portable benchtop NMR instruments for forensic drug identification.

Study at a glance

Characteristics Experimental analysis Peer reviewed
Population Seven 2C-X series new psychoactive substances
Keywords 1h Benchtop nmr Phenylethylamine Drug identification nps Nmr spectroscopy nmr
Citations 5
Key finding Benchtop 60 MHz 1H NMR spectroscopy can differentiate seven 2C-X series NPS based on their proton NMR spectra and structural relationships.

Abstract

The dissemination of spectral information of new psychoactive substances (NPS) acquired on benchtop nuclear magnetic resonance (NMR) spectrometers is of high importance considering the emerging application of such portable and accessible instruments in forensic analyses. Seven members of the 2C-X series (2C-B, 2C-C, 2C-D, 2C-E, 2C-P, 2C-T2, and 2C-T7) of NPS were analyzed via 60 MHz 1 H benchtop NMR spectroscopy and their molecular structural relations are discussed with respect to the observed proton NMR spectra.

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