Response of cluster headache to psilocybin and LSD
Neurology – June 26, 2006
Source: OpenAlex
Summary
Psychedelics and Drug Studies offer compelling hope for cluster headache. Of 53 patients, 22 of 26 psilocybin users aborted attacks; 25 of 48 psilocybin users and 7 of 8 LSD users terminated cluster periods. Psilocybin (18/19) and LSD (4/5) also extended remission. This highlights a novel area in Medicine and Complementary and Alternative Medicine Studies for Migraine and Headache Studies. Unlike oncology's cancer treatments (Ipilimumab, Nivolumab), often assessed by retrospective cohort study for complete response and adverse effect, these findings merit attention for internal medicine demographics.
Abstract
The authors interviewed 53 cluster headache patients who had used psilocybin or lysergic acid diethylamide (LSD) to treat their condition. Twenty-two of 26 psilocybin users reported that psilocybin aborted attacks; 25 of 48 psilocybin users and 7 of 8 LSD users reported cluster period termination; 18 of 19 psilocybin users and 4 of 5 LSD users reported remission period extension. Research on the effects of psilocybin and LSD on cluster headache may be warranted.