Hallucinogen persisting perception disorder after psilocybin consumption: a case study

European Psychiatry  – June 18, 2005

Source: OpenAlex

Summary

An 18-year-old experienced persistent perceptual disturbances for over eight months after psilocybin and cannabis intoxication, underscoring a critical Psychiatry concern. This condition, Hallucinogen Persisting Perception Disorder (HPPD), involves flashbacks without acute drug use, causing profound psychosocial distress. Psychology recognizes these perception changes can endure for five years or more. Such cases inform Psychedelics and Drug Studies, highlighting the complex Neurotransmitter Receptor Influence on Behavior and the importance of Forensic Toxicology and Drug Analysis for understanding hallucinogen effects.

Abstract

Abstract The recurrence of flashbacks without acute or chronic hallucinogen consumption has been recognized in the DSM IV criteria as the hallucinogen persisting perception disorder (HPPD). Perceptual disturbances may last for 5 years or more and represent a real psychosocial distress. We reported here a case of a 18-year-old young man presenting HPPD after a mixed intoxication with psylocibin and cannabis. This report shows symptomatic recurrences persisting more than 8 months. Various differential diagnoses were evoked and our therapeutic strategies were described.

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