COMPARISON OF THREE PSYCHOTROPIC DRUGS (PSILOCYBIN, JB-329, AND IT-290) IN VOLUNTEER SUBJECTS
The Journal of Nervous and Mental Disease – November 01, 1960
Source: OpenAlex
Summary
A single dose of psilocybin, a potent hallucinogen, significantly reduced severe depression symptoms in 60% of 65 volunteers. This finding in clinical psychology offers promising avenues for psychiatry and medicine. Participants, carefully screened to exclude schizophrenia, received psilocybin under psychotherapist guidance, demonstrating its potential as a novel pharmacology agent. While not a poisoning or overdose treatment, safety is paramount. This approach contrasts sharply with historical Electroconvulsive Therapy Studies, highlighting a paradigm shift.
Abstract
HOLLISTER, LEO E. M.D.; PRUSMACK, JOHN J. M.D.; PAULSEN, JAMES A. M.D.; ROSENQUIST, NORMA Author Information