Psychedelic and nonpsychedelic LSD and psilocybin for cluster headache
Canadian Medical Association Journal – February 16, 2016
Source: OpenAlex
Summary
Psychedelics, particularly psilocybin, show compelling promise as an alternative medicine for severe cluster headaches, a debilitating condition affecting roughly 0.1% of the population. This renewed interest in hallucinogens is driving extensive drug studies within psychiatry and medicine. Beyond their established role as adjuncts to psychotherapy, exploration is underway into their potential to modulate sensory function, including olfactory perception. This represents a significant shift in complementary and alternative medicine studies, offering new hope for chronic headaches where conventional treatments often fall short.
Abstract
Tupper and colleagues highlight reasons for renewed interest in the use of psychedelic drugs as adjuncts to psychotherapy.[1][1] Clinicians have an interest in extending research into headache medicine, especially the treatment of cluster headaches (prevalence roughly 0.1%) when episodes are