Analysis of Aeruginascin in Fruit Bodies of the Mushroom Inocybe aeruginascens
International Journal of Crude Drug Research – January 01, 1989
Source: OpenAlex
Summary
A unique compound, aeruginascin, appears to consistently induce euphoria during the ingestion of certain mushrooms. An investigation into ten fruit bodies of *Inocybe aeruginascens*, an Agaricales species, revealed aeruginascin present in similar concentrations to the potent hallucinogen psilocybin. This finding in Fungal Biology suggests aeruginascin modifies psilocybin's pharmacological action. Psychedelics and Drug Studies could explore the Chemistry of these alkaloids, potentially informing chemical synthesis for therapeutic applications, ensuring predictable, positive experiences.
Abstract
Analysis of ten fruit bodies of Inocybe aeruginascens Babos revealed a content of the indole derivative aeruginascin which was in the same order of magnitude as the amounts of psilocybin or baeocystin. There was a correlation between the content of psilocybin, baeocystin and aeruginascin. Aeruginascin seems to modify the pharmacological action of psilocybin to give an always euphoric mood during ingestion of the mushrooms.