Mushroom bioactives—polysaccharides to psilocybin: a viewpoint on the therapeutic use of mushrooms for consumers and patients for health and neuroplasticity
Translational Food Sciences – January 01, 2025
Source: OpenAlex
Summary
Psilocybin-containing mushrooms show compelling potential to aid trauma and foster neuroplasticity, sparking renewed interest in complementary and alternative medicine studies. Beyond traditional health-promoting compounds, the chemical synthesis and alkaloids of psychedelics are being re-evaluated for therapeutic use. Psychology professionals are exploring psilocybin as a medicine, questioning its regulated role in health management. This debate asks if these mushroom-derived compounds should be integrated into mainstream medicine, considering necessary safeguards for such drug studies.
Abstract
Abstract The use of mushrooms in health-promoting foods and substances is widely studied. There are compelling data to indicate that polysaccharides and phenolic compounds derived from mushroom sources have long-lasting metabolic effects when ingested. More recently, attention has returned to the traditional practices of using psychotropic bioactive ingredients obtained from mushrooms for the aid of the treatment of trauma and neuroplasticity therapeutic uses in alternative health practices. While this is heavily legislated and not universally accepted in all of the governments in the world, clinicians and psychotherapy professionals are reimagining the safe and controlled use of these substances (namely psilocybin-based compounds) for health management procedures. This short viewpoint article poses the question, aiming to create a debate of the potential use, as to whether these polysaccharides and psilocybin compounds could, or even should, have an alchemical role to play for consumers and patients in terms of health and neuroplasticity in therapeutic use as foods or medicines? What level of regulation would be required? And what safeguards should be implemented?