Poisoning by hallucinogenic mushroom Hikageshibiretake (Psilocybe argentipes K. Yokoyama) indigenous to Japan.

The Tohoku Journal of Experimental Medicine  – January 01, 1986

Source: OpenAlex

Summary

In five cases of mushroom poisoning involving the psilocybin-containing *Psilocybe argentipes*, severe psychological reactions emerged. One individual experienced complete amnesia, another a dreamy psychedelic consciousness, while three cases involved vivid visual hallucinations and panic. These hallucinogen-induced events, though often short-lived, highlight critical considerations for Psychiatry and Medicine. Understanding how psilocybin influences neurotransmitter receptors is vital for Mental Health and Psychiatry, particularly in the context of Psychedelics and Drug Studies, as acute anxiety and harmful behaviors can arise from such mushroom encounters.

Abstract

Five cases of poisoning by indigenous mushroom Hikageshibiretake (Psilocybe argentipes) are reported. As this mushroom contains psilocybin, in general, clinical features were similar to those seen by pure psilocybin. Acute toxic stuporous state with complete amnesia in the culminating period occurred in one case, psychedelic state with dreamy consciousness in one case and psychotic adverse reactions with vivid visual hallucinations with consciousness in three cases. There were accompanied with anxiety and panic reactions to subjective experiences. Though these toxic effects were usually short-lived, for management of such patients it is important to recognize that horrible emotional reactions and other harmful behavioral problems can also occur.

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