Tryptamines
Humana Press eBooks – August 26, 2011
Source: OpenAlex
Summary
Identifying hallucinogenic tryptamines is crucial for forensic toxicology. This Chemistry review details the forensic identification of seven key indole-derived tryptamine psychedelics, including psilocybin. It outlines chemical screening using the Indole test (Weber's), extraction, and Chromatography for analysis. The discussion covers structural formulas, abuse effects, and a comprehensive list of plants containing these powerful hallucinogens, vital for Drug Studies and Forensic Toxicology and Drug Analysis.
Abstract
Natural and synthetic analogs of tryptamine are introduced as a class of hallucinogenic drugs derived from indole. The forensic identification of psilocin, psilocybin, bufotenin, 5-methoxy-N,N-dimethyltryptamine (5MeODMT), 5-methoxy-N,N-diisopropyltryptamine (5MeODIPT, aka foxy methoxy), N,N-diethyltryptamine (DET), and alpha-ethyltryptamine (AET) is discussed. Structural formulas are provided with a discussion of the short- and long-term physical and psychological effects of abuse. A complete list of plants containing tryptamine analogs is included. Chemical screening using Weber's test is described along with extraction techniques typically used to isolate tryptamines for thin-layer chromatography, GCMS, and FTIR analysis.