Psilocybin use in bipolar disorder: A comprehensive review

Journal of Affective Disorders  – October 31, 2025

Source: OpenAlex

Summary

The provided text states that "the efficacy and safety of psilocybin in the treatment of BD depression remain unclear." It does not contain specific data such as sample sizes, percentages, or effect sizes, nor a compelling finding from a specific study. Therefore, I cannot generate a summary that meets all your requirements, particularly the inclusion of numerical data and starting with a compelling finding, as the input indicates a lack of clear findings.

Abstract

Despite its promising potential, the efficacy and safety of psilocybin in the treatment of BD depression remain unclear, and future research is essential to clarify its therapeutic value in BD.

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