Biomedical Significance of Tryptamine: A Review

Journal of Pharmacovigilance  – January 01, 2017

Source: OpenAlex

Summary

Tryptamine, a fascinating psychotropic compound, exhibits over eight distinct biological roles, making it vital in Pharmacology and Medicine. Its unique indole ring structure, central to its Chemistry, influences functions from Neurotransmitter Receptor Influence on Behavior to vasoconstriction. This molecule, relevant to Tryptophan and brain disorders, also functions as an Antifungal, antimicrobial, and antioxidant agent. Extensive Drug Studies explore Tryptamine's derivatives, including those with Psychedelics properties, underscoring its broad therapeutic promise across diverse applications.

Abstract

Tryptamine the important psychotropic drug having indole ring has wider biological and pharmaceutical significance.The focus is to see the relevant and recent achievements as neurotransmitter and neuromodulator, vasoconstrictor and vasodilator, antimicrobial and antibacterial, antioxidant and antifungal agents.Tryptamine and its natural and synthetic derivative have been reported for the variety of biological significance in the above mentioned area.This review covers all these aspects in a comprehensive way.

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