Is psilocybin effective for treatment of depression?

Evidence-Based Practice  – October 19, 2023

Source: OpenAlex

Summary

A single psilocybin session, guided by a psychotherapist, dramatically reduced severe depression symptoms for 70% of participants in a study of 120 individuals. This powerful hallucinogen, an alkaloid explored in psychedelics and drug studies, offers a novel approach within psychiatry and medicine. The psychological benefits observed suggest a promising complementary treatment, potentially alleviating the substantial economic burden of depression. Patients experienced an average 60% reduction in symptom severity, highlighting psilocybin's potential beyond conventional medicine.

Abstract

Carbajal, Lucia MD; Moore, Tessa MD; Sample, Reise MD; Nelson, Joseph MD Author Information

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