Prolonged hallucinogenic effects following Psilocybe cubensis ingestion: Case report
The poison. – June 30, 2025
Source: OpenAlex
Summary
Weeks after Psilocybin ingestion, a powerful hallucinogen, one documented case experienced prolonged perceptual disturbances and flashbacks, necessitating psychopharmacological intervention. This highlights potential neuropsychiatric symptoms. Though traditional medicine has historical uses for psychedelics, modern pharmacology, especially in drug studies of alkaloid synthesis and pharmacology, must fully grasp these risks. Psychology plays a vital role in managing such effects, underscoring the need for individualized care and enhanced harm reduction strategies amidst growing recreational use.
Abstract
Psilocybe cubensis is a widely used psilocybin-containing mushroom with well-documented acute psychoactive effects. We report a case of prolonged perceptual disturbances and flashbacks occurring weeks after ingestion, requiring psychopharmacological intervention. This case illustrates the potential for persistent neuropsychiatric symptoms following psilocybin intoxication and highlights the need for individualized treatment approaches. Given the increasing recreational use of psilocybin, enhanced harm reduction strategies and expanded clinical research are essential for effective management.