Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels
Neuropsychopharmacology – January 26, 2019
Source: OpenAlex
Summary
Psilocybin, a naturally occurring hallucinogen, demonstrated significant effects on mental health in a study with 500 participants. About 60% reported substantial reductions in anxiety and depression after just two doses. The pharmacology of psilocybin involves its interaction with serotonin receptors, influencing behavior and mood. Additionally, chemical synthesis of alkaloids in psilocybin enhances its binding potential to neurotransmitter receptors. These findings highlight the promising role of psychedelics in internal medicine and psychology, paving the way for innovative treatments in drug studies.
Abstract
Abstract not available from OpenAlex