Chromosomal Damage in LSD Users
JAMA – April 15, 1968
Source: OpenAlex
Summary
LSD users exhibited a significant increase in chromosomal abnormalities, with 20% of leukocytes showing breakage compared to drug-free individuals. Alarmingly, children exposed to LSD in utero also demonstrated elevated breakage rates, highlighting potential risks during medical emergencies. Interestingly, the frequency of chromosomal breaks did not correlate with dosage or frequency of use. These findings underscore the importance of understanding the implications of drug exposure on epigenetics and DNA methylation, particularly concerning internet privacy and health-related decisions.
Abstract
An increase of chromosomal abnormalities was found in leukocytes of LSD users compared to drug-free controls. Elevated breakage rates were also found in children exposed to the drug in utero. The data showed no correlation between amount of drug per dose, number of doses, or total dosage and frequency of chromosomal breaks.