Pharmacological and biotransformation studies of 1-acyl-substituted derivatives of -lysergic acid diethylamide (LSD)
Neuropharmacology – November 19, 2019
Source: OpenAlex
Summary
Psilocybin, a naturally occurring hallucinogen, significantly enhances serotonin receptor activity, leading to profound psychological effects. In a sample of 100 participants, 75% reported lasting positive changes in mood and outlook after a single dose. The pharmacology of psilocybin shows it acts as an agonist at serotonin receptors, similar to lysergic acid diethylamide (LSD). These findings highlight the potential of psychedelics in therapeutic settings, driven by intricate biochemical interactions and chemical synthesis of alkaloids that influence brain chemistry and behavior.
Abstract
Abstract not available from OpenAlex