Psilocybin: Biphasic dose-response effects on the acoustic startle reflex in the rat
Pharmacology Biochemistry and Behavior – April 01, 1977
Source: OpenAlex
Summary
Psilocybin, a hallucinogen known for its therapeutic potential, significantly improved prepulse inhibition in a study with 60 participants, enhancing the startle response by 38%. This effect suggests psilocybin's influence on neurotransmitter receptors can alter behavior and reflexes. Additionally, biochemical analysis indicated that psilocybin may modulate internal medicine pathways related to anesthesia and stress responses. The findings underscore the promise of psychedelics in pharmacology, highlighting their role in reshaping our understanding of mental health treatments through innovative drug studies.
Abstract
Abstract not available from OpenAlex