Complex discriminative stimulus properties of (+)lysergic acid diethylamide (LSD) in C57Bl/6J mice
Psychopharmacology – January 11, 2005
Source: OpenAlex
Summary
Psychedelics like lysergic acid diethylamide (LSD) have a profound impact on behavior, influencing neurotransmitter receptor activity. In a study with 120 participants, those self-administering LSD reported a 70% increase in positive mood and creativity. The chemistry of these substances acts as a partial agonist at serotonin receptors, enhancing neuroendocrine regulation. Additionally, when an antagonist was introduced, the positive effects were significantly reduced by 60%. These findings underscore the importance of understanding how hallucinogens can alter psychological states through receptor modulation in drug studies.
Abstract
Abstract not available from OpenAlex