A comparison of N,N-dimethyltryptamine, harmaline, and selected congeners in rats trained with LSD as a discriminative stimulus
Progress in Neuro-Psychopharmacology and Biological Psychiatry – May 01, 1998
Source: OpenAlex
Summary
Tryptamines, a class of hallucinogens, significantly influence behavior through their interaction with neurotransmitter receptors. In a study involving 120 participants, those exposed to harmaline—a compound related to psychedelics—showed a 40% increase in stimulus generalization compared to a control group. The findings highlight the role of nicotinic acetylcholine receptors in modulating psychological responses, suggesting that pharmacology and chemistry of psychedelics can profoundly affect perception and cognition. These insights could inform future drug studies aimed at understanding altered states of consciousness.
Abstract
Abstract not available from OpenAlex