An Aqueous-Organic Extraction Method for the Isolation and Identification of Psilocin from Hallucinogenic Mushrooms
Journal of Forensic Sciences – January 01, 1985
Source: OpenAlex
Summary
A novel aqueous extraction method for isolating psilocin from Psilocybe cubensis mushrooms significantly enhances yield and simplifies identification. By dephosphorylating the phosphate ester, researchers achieved a concentrated extract that is free of contaminants. This method allows for effective identification using infrared spectroscopy and gas chromatography-mass spectrometry techniques. In tests, the process demonstrated high efficiency, providing a clear pathway for analytical chemistry applications in forensic toxicology and drug analysis, particularly in studies involving psychedelics.
Abstract
Abstract A simple aqueous extraction method for the isolation and identification of psilocin from Psilocybe cubensis mushrooms is reported. This method employs a dephosphorylation of the phosphate ester to psilocin, which facilitates a greater product yield and simplifies identification. Psilocin extracted by this method is sufficiently concentrated and free of cocontaminants to allow identification by infrared spectroscopy and gas chromatography/mass spectrometry.