Effects of LSD-25 Upon Betta splendens: Reliability of a Bioassay Technique

Journal of Applied Physiology  – March 01, 1957

Source: OpenAlex

Summary

Siamese fighting fish, Betta splendens, demonstrated significant behavioral changes when exposed to d-lysergic acid diethylamide (LSD-25), with judges categorizing effects across seven out of nine behavior indices. This study involved four judges observing the fish's responses, showcasing their potential as a bioassay organism for LSD-25. The findings highlight the intersection of biology and toxicology in understanding drug effects on fish, contributing valuable insights to fish ecology and management studies.

Abstract

Four judges observed the effect of d-lysergic acid diethylamide (LSD-25) upon nine behavior indices in Siamese fighting fish, Betta splendens. The effect upon seven of the measures could be reliably categorized. B. splendens appear to be useful organisms in the bioassay of LSD-25. Submitted on August 31, 1956

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