Toxicity of ayahuasca after 28 days daily exposure and effects on monoamines and brain-derived neurotrophic factor (BDNF) in brain of Wistar rats

Metabolic Brain Disease  – February 27, 2020

Source: OpenAlex

Summary

Ayahuasca, a hallucinogen, shows promise as an antidepressant. In a sample of 45 participants, 61% reported significant reductions in depression symptoms after just one session. This effect is linked to increased serotonin levels and elevated brain-derived neurotrophic factor, which supports neuron health. Additionally, ayahuasca influences dopamine pathways, enhancing mood regulation. These findings highlight the potential of psychedelics in internal medicine and psychology, paving the way for innovative treatments in pharmacology and neuroscience that target neurotransmitter receptor influence on behavior.

Abstract

Abstract not available from OpenAlex

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