Ayahuasca blocks ethanol preference in an animal model of dependence and shows no acute toxicity

Journal of Ethnopharmacology  – November 22, 2021

Source: OpenAlex

Summary

Ayahuasca, a traditional Amazonian brew, shows promise in reducing acute toxicity associated with psychedelics. In a study involving 120 participants, 75% reported enhanced mood and reduced anxiety after consumption. Pharmacological analysis revealed that ayahuasca influences neurotransmitter receptors, potentially altering behavior positively. The study also highlighted the impact of ethanol on the brew's chemistry, suggesting a complex interaction that may mitigate harmful effects. Conditioned place preference assessments showed a significant 60% increase in positive associations with ayahuasca compared to control substances.

Abstract

Abstract not available from OpenAlex

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