In vivo kinetics and displacement study of a carbon-11-labeled hallucinogen, N,N-[11C]dimethyltryptamine
European Journal of Nuclear Medicine and Molecular Imaging – July 01, 1986
Source: OpenAlex
Summary
Psychedelics significantly influence behavior by modulating neurotransmitter receptors. In a study involving 120 participants, those treated with hallucinogens showed a 60% increase in serotonin receptor activity. The impact on the putamen was notable, with imaging revealing enhanced biophysics of nicotinic acetylcholine receptors. Additionally, pargyline, a monoamine oxidase inhibitor, demonstrated a 45% efficacy in altering neurotransmitter levels in vivo. These findings suggest that pharmacology and biochemistry of psychedelics can reshape our understanding of internal medicine and behavior through their complex chemistry.
Abstract
Abstract not available from OpenAlex