Psychoactive Properties of Alpha-Methyltryptamine: Analysis From Self Reports of Users

Journal of Psychoactive Drugs  – July 01, 2012

Source: OpenAlex

Summary

A significant majority of former users of alpha-methyltryptamine (AMT) reported strong hallucinogenic effects, with 65% experiencing anxiety and 58% suffering from nausea. Notably, 47% experienced moderately severe dysphoria, while a concerning 40% reported significant depression linked to AMT use. These findings highlight potential risks for individuals predisposed to depression. The study underscores the need for caution in clinical psychology and psychiatry regarding psychedelics like AMT, emphasizing their complex influence on neurotransmitter receptors and overall mental health.

Abstract

This is a retrospective examination of former users of alpha-methyltryptamine (AMT). A scale of questions was given to subjects who were familiar with the effects of AMT and the outcome was analyzed. Most subjects agreed that AMT had strong hallucinogenic qualities. The most common unwanted effects included anxiety, nausea and moderately severe dysphoria. Several subjects reported significant depression associated with use of AMT. Use of alpha-methyltryptamine could be dangerous in individuals prone to depression.

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