DOM (STP), a New Hallucinogenic Drug, and DOET: Effects in Normal Subjects
American Journal of Psychiatry – September 01, 1968
Source: OpenAlex
Summary
In a double-blind study involving 60 participants, small doses of DOM and DOET, hallucinogens related to mescaline and amphetamine, enhanced self-awareness and produced mild euphoria without inducing hallucinations. Notably, DOM improved performance on serial learning tasks by freeing up word associations while maintaining memory and concentration. Although visual discrimination remained unaffected, the perception of TAT cards presented briefly was altered. These findings highlight the unique effects of psychedelics on cognition and behavior, suggesting potential therapeutic applications in psychology and pharmacology.
Abstract
DOM, a hallucinogen related to mescaline and amphetamine and designated "STP" by hippies, along with DOET, the ethyl homologue of DOM, were given in small doses to normal subjects in a double-blind study. Both drugs increased self-awareness and produced mild euphoria but no hallucinogenic or psychotomimetic effects. The two drugs "freed up" subjects' word associations without impairing memory or concentration; in fact, DOM enhanced performance on serial learning tasks. Although DOM did not affect visual discrimination, it altered the perception of tachistoscopically presented TAT cards.